Micro crystalline cellulose powder (MCCP) is made from purified partially depolymerised Alfa cellulose relatively free from both organic and inorganic contaminants . It is insoluble in water, dilute acids, common organic solvents and oils, Partially soluble with swelling in dilute alkali. It is fine, whitodour less, edible and metabolically inert powder.

MICROCRYSTALLINE CELLULOSE POWDER CONFORMS THE STANDARDS OF IP, BP, EP, USP

APPLICATIONS

Microcrystalline cellulose is using for tableting operations is shown by the number and variety of functions it can perform


DIRECT COMPRESSION

  • Binder

  • Disintigrant

  • Flow aid

  • Filler

WET GRANULATION

  • Permits fast addition of granulation fluid

  • Binder

ADVANTAGES OF USING MICROCRYSTALLINE CELLULOSE

  • Low friability

  • Non desiccating

  • High compressible even with problem formulations

DIFFERENT GRADES OF MCCP AND TYPICAL PHYSICAL PROPERTIES
Grade Avg Particle size (mm)
Uses
101 50 Standard grade widely used for direct compression And wet granulation.
102 100 Larger particle size for better flowability like direct Compression tableting and wet granulation
103 50 Low moisture grade ideal for moisture sensitive Products.
105 20 Finest particle size for direct compression.
112 90 Low moisture grade with larger particle size. It also allows formulating directly compressible Moisture sensitive actives.
113 50 Low moisture grade useful with moisture sensitive Materials.
200 180 Coarsest Particle size available for direct compression And dry granulation.
301 50 High density grade mainly for smaller tablets.
302 90 High density with large particle size mainly for thin Tablets.


PHYSICAL AND CHEMICAL PROPERTIES OF MCCP -101 BP/USP/EP/IP
Characteristics IP BP USP EP
Description Fine/Granular, White, Odourkess Powder. Fine/Granular, White, odourless Powder Fine, Granular, White, odourless Powder Fine, Granular, White, Odourless Powder.
Solubility Complies Complies Complies Complies
Identification Complies Complies Complies Complies
PH 5.0-7.0 5.0-7.5 5.0-7.0 5.0-7.5
Starch & Dextrin Absent Absent Absent Absent
Organic Impurities Absent Absent Absent Absent
Water Soluble Substance, % Max. 0.20 0.20 0.24 0.20
Arsenic, ppm Max 2 2 2 2
Heavy metals, ppm Max 10 10 10 10
Sulphated Ash 0.20 0.10 0.05 0.10
Loss on drying, % Max 6.0 7.0 6.0 6.0
Assay (on dried basis) % Min. 97-102 97-102 97-102 97-102
Eather Soluble Substance % Max N.A 0.05 0.05 0.05
Bulk Density, gm/cc   Loose As per requirement As per requirement As per requirement As per requirement
Tapped As per requirement As per requirement As per requirement As per requirement
Sieve Analysis, Wt% (+) 60 Mesh NMT 1 % NMT 1% NMT 1% NMT 1%
(+) 100 Mesh        
(+) 200 Mesh NMT 30% NMT 30% NMT 30% NMT 30%
MICROBIAL LIMITS        
Total Aerobic Microbial Count CFU per Gram Max. N.A 1000 1000 1000
Total Combined Mold & Yeasts Count, CFU per Gram Max. N.A. 100 100 100
Escherichia coli N.A. Absent Absent Absent
Salmonella species N.A. Absent Absent Absent
Staphylococcus Aureus N.A. Absent Absent Absent
Psuedomonas Aeruginosa N.A. Absent Absent Absent
 

PHYSICAL AND CHEMICAL PROPERTIES OF MCCP - 102 BP/USP/EP/IP
Characteristics IP BP USP EP
Description Fine/Granular, White, Odourkess Powder. Fine/Granular, White, odourless Powder Fine, Granular, White, odourless Powder Fine, Granular, White, Odourless Powder.
Solubility Complies Complies Complies Complies
Identification Complies Complies Complies Complies
PH 5.0-7.0 5.0-7.5 5.0-7.0 5.0-7.5
Starch & Dextrin Absent Absent Absent Absent
Organic Impurities Absent Absent Absent Absent
Water Soluble Substance, % Max. 0.20 0.20 0.24 0.20
Arsenic, ppm Max 2 2 2 2
Heavy metals, ppm Max 10 10 10 10
Sulphated Ash 0.20 0.10 0.05 0.10
Loss on drying, % Max 6.0 7.0 6.0 6.0
Assay (on dried basis) % Min. 97-102 97-102 97-102 97-102
Eather Soluble Substance % Max N.A 0.05 0.05 0.05
Bulk Density, gm/cc   Loose As per requirement As per requirement As per requirement As per requirement
Tapped As per requirement As per requirement As per requirement As per requirement
Sieve Analysis, Wt% (+) 60 Mesh NMT 8 % NMT 8% NMT 8% NMT 8%
(+) 100 Mesh        
(+) 200 Mesh NLT 45% NLT 45% NLT 45% NLT 45%
MICROBIAL LIMITS        
Total Aerobic Microbial Count CFU per Gram Max. N.A 1000 1000 1000
Total Combined Mold & Yeasts Count, CFU per Gram Max. N.A. 100 100 100
Escherichia coli N.A. Absent Absent Absent
Salmonella species N.A. Absent Absent Absent
Staphylococcus Aureus N.A. Absent Absent Absent
Psuedomonas Aeruginosa N.A. Absent Absent Absent
 

APLICATION USER : 1.        FOODS 2.        COSMETICS 3.        PHARMACEUTICALS 4.        ANIMAL HEALTH PRODUCTS PACKING :   Packed in 25 Kg HDPE Bags with Liner inside FILTER AID CELLULOSE:

It finds application as an effective filter media for achieving very low levels of suspended impurities (i.e. in PPB levels) especially where clarity of liquids is a criterion. It is established as an outstanding filter medium for chloro alkali plants with membrane technology for filteration.

SPECIFICATION OF FILTER AID CELLULOSE

CHARECTERISTIC

SPECIFICATION

A. CHEMICAL Description

White/almost white, Odourless, Fluffy powder

      pH

5.0-7.0

      Heavy Metals, ppm Max

10

      Ash Content, % Max

0.20
 

      Loss on drying, % Max

6.0

      Assay (on dried basis) %

97.0
 

B. PHYSICAL

  

      Bulk Density, gm/cc

  

       Loose

0.15 - 0.25

      Sieve Analysis, Wt.%

  

          (+) 40 Mesh

  

          (+) 60 Mesh

  

          (+) 100 Mesh

  

          (+) 200 Mesh

  

          (-) 300 Mesh

  
 
 
Note:    1.  NMT - Not more than, NLT - Not Less than
            2.  Bulk Density & Sieve Analysis are as per consignee's requirements
PACKING:  Filter Aid Cellulose is packed in 25 Kg HDPE Bags with Liner inside.
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